Modeling protein crystal growth through helical pseudosymmetry

Protein Crystal Growth

Numerical Modeling of Czochralski Silicon Crystal Growth

Modeling of heat transfer is presented for the entire Czochralski Si-growth furnace. The axisymmetric steady-state approach with moving computational grids is used. Melt turbulent flow, inert gas flow, heat transfer in solid parts, and radiative heat transfer in the system are considered. The Reynolds-averaged Navier-Stokes equations written with the Boussinesq approximation and the energy equa...

Logistic Regression for Crystal Growth Process Modeling through Hierarchical Nonnegative Garrote based Variable Selection

Logistic Regression for Crystal Growth Process Modeling through Hierarchical Nonnegative Garrote based Variable Selection Hongyue Sun, Xinwei Deng, Kaibo Wang, and Ran Jin Grado Department of Industrial and Systems Engineering, Virginia Tech., Blacksburg, VA 24061, USA Department of Statistics, Virginia Tech., Blacksburg, VA 24061, USA Department of Industrial Engineering, Tsinghua University, ...

Microrobotic Streak Seeding For Protein Crystal Growth

We present a microrobotic system for protein crystal micromanipulation tasks. The focus in this paper is on the task known to crystallographers as streak seeding – it is used to entice certain protein crystals to grow. Our system features a set of custom designed micropositioner end-effectors we call microshovels to replace traditional tools used by crystallographers for this task. We have used...

Modeling transmembrane helical oligomers.

Recently, methods for the analysis and design of water-soluble, oligomeric bundles of alpha helices, including coiled coils, have reached a high level of sophistication. These same methods may now be applied to transmembrane helical bundles. Studies of the transmembrane domains of glycophorin, phospholamban, and the M2 protein from influenza A virus exemplify this general approach.